Complex matrix for biomedical use

C - Chemistry – Metallurgy – 08 – B

Patent

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Details

C08B 37/00 (2006.01) A61K 31/728 (2006.01) A61L 27/14 (2006.01) A61L 27/20 (2006.01) A61L 27/26 (2006.01) A61L 27/52 (2006.01) A61L 27/58 (2006.01) A61L 31/04 (2006.01) C08L 5/08 (2006.01)

Patent

CA 2534033

The invention concerns a complex matrix consisting of at least one crosslinked biocompatible polymer of natural origin whereon are grafted small chains of molecular weight less than 50000 Da with a grafting rate between 10 and 40 %, as well as a method for preparing a hardly degradable biocompatible matrix consisting of at least one polymer of natural origin, which consists in: grafting small chains of molecular weight less than 10000 Da, with a grafting rate between 10 and 40 %, and in mutually crosslinking the main chains of the polymer, to create a homogeneous matrix.

L'invention concerne une matrice complexe constituée d'au moins un polymère biocompatible d'origine naturelle, réticulée et sur laquelle sont greffées des petites chaînes de poids moléculaire inférieur à 50 000 Da avec un taux de greffage de 10 à 40 %, ainsi qu'un procédé de préparation d'une matrice biocompatible peu dégradable constituée d'au moins un polymère d'origine naturelle, consistant : d'une part, à greffer de petites chaînes de poids moléculaire inférieur à 10 000 Da, avec un taux de greffage de 10 à 40 %, d'autre part, à réticuler les chaînes principales du polymère entre elles, pour créer une matrice homogène.

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