Complex of dideoxynucleoside and phosphonoformic acid

Details Complex of dideoxynucleoside and phosphonoformic acid Complex of dideoxynucleoside and phosphonoformic acid

C - Chemistry, Metallurgy

07

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C07H 19/10 (2006.01) A61K 31/70 (2006.01) C07H 19/20 (2006.01)

Patent

CA 2042242

60412-2146 ABSTRACT OF THE DISCLOSURE Compounds having the structure Image in which R is alkyl, aryl, or aralkyl, A is hydrogen, lower alkyl or a water-soluble cation, s is hydrogen, fluorine, or azido, the bond Image is saturated when B is fluorine or azido and is saturated or unsaturated when B is hydrogen, and D is a purine or pyrimidine base are effective inhibitors of retrovirus replication.

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