Complex of polymeric quaternary ammonium and anionic...

A - Human Necessities – 01 – N

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A01N 47/44 (2006.01) A01N 33/12 (2006.01) A01N 43/04 (2006.01) A01P 1/00 (2006.01) A61L 12/14 (2006.01)

Patent

CA 2755106

Disclosed herein are ophthalmic solutions and methods of using the solutions which comprise a complex of at least one cationic component and an anionic polymer, wherein the complex can be used as an antimicrobial agent. The solutions described have complexes which can be dissolved in aqueous ophthalmic solutions due to both lower charge load and lower total polymer concentrations than commonly taught. The complexes display different antimicrobial profiles than the non-complexed antimicrobial agents.

L'invention concerne des solutions ophtalmiques ainsi que des procédés d'utilisation des solutions qui comprennent un complexe d'au moins un composant cationique et un polymère anionique; le complexe peut servir d'agent antimicrobien. Les solutions selon l'invention présentent des complexes que l'on peut dissoudre dans des solutions ophtalmiques aqueuses du fait à la fois de charges inférieures et de concentrations polymères totales inférieures par rapport à ce qui est généralement admis. Les complexes affichent différents profils antimicrobiens comparés aux agents antimicrobiens non complexés.

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