Complex suitable for carrying out a method of purifying...

Details Complex suitable for carrying out a method of purifying... Complex suitable for carrying out a method of purifying...

C - Chemistry, Metallurgy

07

K

167/134, 167/37,

C07K 17/10 (2006.01) A61K 39/29 (2006.01) C07K 1/14 (2006.01) C07K 14/02 (2006.01) G01N 33/576 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2025263

ABSTRACT OF THE DISCLOSURE: There is disclosed a complex comprised of an insoluble polymer carrier to which monomeric human albumin is covalently bound and of a pre-S hepatitis B surface antigen bound in an elutable form to the monomeric human albumin by its pre-S(2)- and/or pre-S(1)-region. This complex may be used for therapeutic and diagnostic purposes and enables the rapid and efficient purification of pre-S-HBsAg by affinity chromatography.

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