Complexes of paroxetine, with cyclodextrines or cyclodextrin...

Details Complexes of paroxetine, with cyclodextrines or cyclodextrin... Complexes of paroxetine, with cyclodextrines or cyclodextrin...

C - Chemistry, Metallurgy

07

D

C07D 405/12 (2006.01) A61K 31/445 (2006.01) A61K 31/4525 (2006.01) A61P 25/00 (2006.01) C08B 37/00 (2006.01)

Patent

CA 2341984

Complexes of paroxetine, as free base or salt, with a cyclodextrin or a cyclodextrin derivative having a molar ratio between paroxetine and cyclodextrin ranging from 1:0.25 to 1:20, suitable for use in liquid and solid pharmaceutical compositions for oral and parenteral administration.

L'invention concerne des complexes de paroxétine, utilisés comme base libre ou comme sel, avec une cyclodextrine ou un dérivé de la cyclodextrine, présentant un rapport molaire entre la paroxétine et la cyclodextrine compris entre 1:0,25 et 1:20. Ces complexes conviennent à une utilisation dans des compositions pharmaceutiques liquides et solides pour une administration par voie orale et parentérale.

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