Complexes of prostaglandin derivatives and monosubstituted,...

A - Human Necessities – 61 – K

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A61K 31/5575 (2006.01) A61K 47/40 (2006.01) A61P 27/02 (2006.01) C08K 5/101 (2006.01) C08L 5/16 (2006.01)

Patent

CA 2691491

The present invention relates to water-soluble, non-covalent complexes of a group of prostaglandin derivatives including latanoprost and monosubstituted, charged .beta.-cyclodextrins, as well as uses of these complexes in therapeutic compositions that are administered topically for treating intraocular hypertension and glaucoma.

La présente invention porte sur des complexes non covalents, solubles dans l'eau, d'un groupe de dérivés de prostaglandine comprenant le latanoprost et de ß- cyclodextrines chargées, monosubstitués, ainsi que sur des utilisations de ces complexes dans des compositions thérapeutiques qui sont administrées par voie topique pour le traitement de l'hypertension intraoculaire et du glaucome.

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