Complexes of technetium-99m with propylene amine oximes

Details Complexes of technetium-99m with propylene amine oximes Complexes of technetium-99m with propylene amine oximes

C - Chemistry, Metallurgy

07

F

167/48, 260/428.

C07F 13/00 (2006.01) A61K 51/04 (2006.01)

Patent

CA 1243329

ABSTRACT COMPLEXES OF TECHNETIUM-99m WITH PROPYLENE AMINE OXIMES A family of propylene amine oxime ligands has the formula 2 Image wherein preferably R1 is C1-C4 alkyl or phenyl and each of R, R2, R3 and R4 is H or C1-C4 alkyl. The technetium-99m complexes of these ligands are lipophilic neutral complexes useful as diagnostic radiopharmaceuticals and particularly for brain scanning. The ligands show stereoisomerism. The preparation and properties of the dl- and meso- stereoisomers, and of the d- and l-enantiomers, are described. The l-enantiomer and the dl-stereoisomer of the preferred compound (2, R=R1=R2=CH3, R3=R4=H) show good retention in the brain.

503659

Affiliated with

Also associated with

Rating

Complexes of technetium-99m with propylene amine oximes does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Complexes of technetium-99m with propylene amine oximes, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Complexes of technetium-99m with propylene amine oximes will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1257839