A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/10 (2006.01) A61K 9/16 (2006.01) A61K 47/34 (2006.01)
Patent
CA 2339482
Compositions and methods are provided to control the release of relatively low molecular weight therapeutic species through hydrogels by first dispersing or dissolving such therapeutic species within relatively hydrophobic rate modifying agents to form a mixture. The mixture is formed into microparticles that are dispersed within bioabsorbable hydrogels, so as to release the water soluble therapeutic agents in a controlled fashion. Methods of using the compositions of the present invention in therapeutic systems are also provided.
L'invention concerne des compositions et méthodes de régulation de la libération d'espèces thérapeutiques à poids moléculaire relativement faible grâce à des hydrogels, d'abord par dispersion ou dissolution des ces espèces thérapeutiques dans des agents de modification de vitesse relativement hydrophobes pour former un mélange. Le mélange forme des microparticules qui sont dispersées dans des hydrogels biologiquement absorbables, de manière à libérer de façon régulée les agents thérapeutiques solubles dans l'eau. L'invention concerne également des méthodes d'utilisation des compositions de la présente invention dans des systèmes thérapeutiques.
Incept Llc
Smart & Biggar
LandOfFree
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