Composite molecular system for the contra-escalatory...

C - Chemistry – Metallurgy – 08 – H

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C08H 7/00 (2011.01) A61K 9/08 (2006.01) A61K 31/70 (2006.01) A61K 31/715 (2006.01) A61K 35/10 (2006.01) C08L 97/00 (2006.01)

Patent

CA 2084093

The invention concerns a composite molecular system for use in restitutive chemotherapy against viral infection,, the sys- tem being obtained as follows: (l) preparing lignin units high in polysaccharides (PLP) by: extraction, in weakly acid or alkaline conditions, from wood or wood-like materials and/or from plant-cell cultures (A) in aqueous media; separating off the insoluble solids; (II) preparing low-molecular-weight lignoid units low in polysaccharides (LPL) by: alkaline-aqueous extraction (p11 7-14) from wood-carbonization products or bio-converted wood-like materials (B); separating off the alkali-insoluble solids; (lll) pre- paration of a water-soluble mixed polymer [LD(PLP=LPL)] by: reacting the product of step (I), the lignin units high in polysac- charides (PLP), with the products of step (II) the lignoid units low in polysaccharides (LPL), in alkaline aqueous conditions (pH 9.12, isolating the LD fractions of this HD(PLP = LPL) mixed polymer by ultra- filtration, taking the cut between the nominal values of about 15 and 40 kD and discarding the residue; treating the solution with an H+ Cation-exchange agent at pH 3 to 7.0 and processing the acid LD(LPL = PLP) system. This system can be used in particular as a parenterally or locally applied system against viral infections, including retroviruses, in particular those of the HIV type, as well as AIDS viruses,

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