Composite organic compound powder for medical use and...

A - Human Necessities – 61 – K

Patent

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A61K 47/32 (2006.01) A61K 9/10 (2006.01) A61K 9/14 (2006.01) A61K 31/192 (2006.01) A61K 31/222 (2006.01) A61K 31/405 (2006.01) A61K 31/41 (2006.01) A61K 31/4174 (2006.01) A61K 31/573 (2006.01) A61K 47/10 (2006.01) A61K 47/12 (2006.01) A61K 47/24 (2006.01)

Patent

CA 2737543

A safe medical agent which is low in contamination by a pulverizing medium, while having improved bioavailabil-ity. A method for producing a composite organic compound powder for medical use, which comprises a step of mixing a poorly water-soluble crystalline organic compound powder, a physiologically acceptable salt, a physiologically acceptable polyol and a carboxyvinyl polymer and pulverizing the organic compound powder, and a step of removing at least the salt and the polyol dur-ing or after the pulverization.

Linvention concerne un agent médical sûr peu contaminé par un milieu de pulvérisation tout en présentant une biodisponibilité améliorée. Linvention concerne également un procédé pour produire une poudre composite de composés organiques à usage médical consistant à : mélanger une poudre cristalline de composés organiques peu solubles dans leau, un sel physiologiquement acceptable, un polyol physiologiquement acceptable et un polymère de carboxyvinyle , et à pulvériser la poudre de composés organiques ; et à éliminer au moins le sel et le polyol pendant ou après la pulvérisation.

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