Composite scaffold with post anchor for the repair and...

A - Human Necessities – 61 – L

Patent

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Details

A61L 27/00 (2006.01) A61F 2/30 (2006.01) A61K 35/12 (2006.01) A61L 27/10 (2006.01) A61L 27/14 (2006.01) A61L 27/42 (2006.01) A61L 27/46 (2006.01) A61L 27/56 (2006.01) B29C 44/12 (2006.01) A61B 17/00 (2006.01) A61B 17/064 (2006.01) A61F 2/00 (2006.01) A61F 2/02 (2006.01) A61F 2/08 (2006.01) A61F 2/28 (2006.01) A61F 2/38 (2006.01) A61F 2/44 (2006.01) A61F 2/46 (2006.01)

Patent

CA 2391697

A prosthetic implant having a tissue scaffold and a fixation device with a scaffold support and an anchoring post. The anchoring post extends from a surface of the scaffold support at a selected angle with the scaffold support embedded within the scaffold. The scaffold has a porous ceramic phase and a porous polymer phase. The polymer is foamed while in solution that is infused in the pores of the ceramic to create a interphase junction of interlocked porous materials and embedding the scaffold support portion of the fixation device. The preferred method for foaming is by lyophilization. The scaffold may be infused or coated with a variety of bioactive materials to induce ingrowth or to release a medicament. The mutilayered porous scaffold can mimic the morphology of an injured tissue junction with a gradient morphology and cell composition.

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