Composite scaffolds and methods using same for generating...

C - Chemistry – Metallurgy – 12 – N

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C12N 5/071 (2010.01) A61K 35/12 (2006.01) A61L 27/14 (2006.01) A61L 27/18 (2006.01) A61L 27/38 (2006.01) A61L 27/40 (2006.01) A61L 27/54 (2006.01) A61L 27/58 (2006.01) C08L 5/02 (2006.01) C08L 67/04 (2006.01) C08L 71/02 (2006.01) C08L 89/00 (2006.01)

Patent

CA 2445523

A composite scaffold for engineering a heterogeneous tissue is provided. The composite scaffold includes: (a) a first scaffold being capable of supporting formation of a first tissue type thereupon; and (b) a second scaffold being capable of supporting formation of a second tissue type thereupon; wherein the first scaffold and the second scaffold are arranged with respect to each other such that when the first scaffold supports the first tissue type and the second scaffold supports the second tissue type, a distance between any cell of the second tissue type and the first tissue type does not exceed 200 $G(m)m.

L'invention concerne un squelette composite pour construire un tissu hétérogène, comprenant: (a) un premier squelette apte à supporter la formation d'un premier type de tissu; et (b) un deuxième squelette apte à supporter la formation d'un deuxième type de tissu. Les premier et deuxième squelette ont une disposition mutuelle telle que, lorsque le premier squelette supporte le premier type de tissu et le deuxième squelette le deuxième type de tissu, la distance entre une cellule quelconque du deuxième type de tissu et le premier type de tissu ne dépasse pas 200 µm.

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