A - Human Necessities – 61 – F
Patent
A - Human Necessities
61
F
A61F 2/06 (2006.01)
Patent
CA 2578581
A composite vascular graft (10) incorporates bioactive agents to deliver therapeutic materials and/or inhibit or reduce bacterial growth during and following the introduction of the graft to the implantation site in a vascular system. A composite vascular graft includes a porous tubular graft member (12). One or more biodegradable, bioactive agent coating layers (14) are disposed over the graft member, the coating layer including at least one bioactive agent (16). A biodegradable sheath (18) is disposed over the coating layer. The sheath has a rigidity greater than the flexible tubular graft member and is biodegradable to expose the coating layer so as to reestablish the flexibility of the tubular graft member.
L~invention porte sur une greffe vasculaire composite (10) comprenant des agents bioactifs pour administrer des matériaux thérapeutiques et/ou présenter ou réduire la croissance bactérienne pendant et après l~introduction de la greffe sur le site d~implantation dans un système vasculaire. Une greffe vasculaire composite comprend un élément de greffe tubulaire poreux (12). Une ou plusieurs couches de revêtement d~agents biodégradables, bioactifs (14) recouvrent l~élément de greffe, la couche de revêtement comportant au moins un agent bioactif (16). Une gaine biodégradable (18) recouvre la couche de revêtement. La gaine a une rigidité supérieure à celle de l~élément de greffe tubulaire flexible et est biodégradable pour exposer la couche de revêtement de façon à rétablir la flexibilité de l~élément de greffe tubulaire.
Boston Scientific Limited
Piasetzki & Nenniger Llp
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