C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 471/04 (2006.01) A61K 31/437 (2006.01) A61K 31/496 (2006.01) A61K 31/497 (2006.01) A61K 31/506 (2006.01)
Patent
CA 2494832
This invention provides compounds having drug and bio-affecting properties, their pharmaceutical compositions and method of use. In particular, the invention is concerned with azaindoleoxoacetyl piperazine derivatives. These compounds possess unique antiviral activity, whether used alone or in combination with other antivirals, antiinfectives, immunomodulators or HIV entry inhibitors. More particularly, the present invention relates to the treatment of HIV and AIDS.
L'invention concerne des composés présentant des propriétés médicamenteuses et bioactives, leurs compositions pharmaceutiques et leur procédé d'utilisation. Cette invention concerne en particulier des dérivés d'azaindoloxoacétyle pipérazine. Ces composés présentent une activité antivirale unique, qu'ils soient utilisés seuls ou en combinaison avec d'autres agents antiviraux, anti-infectieux, immunomodulateurs ou inhibiteurs d'entrée du VIH. La présente invention se rapporte plus particulièrement au traitement du VIH et du SIDA.
Kadow John F.
Matiskella John D.
Meanwell Nicholas A.
Regueiro-Ren Alicia
Ueda Yasutsugu
Bristol-Myers Squibb Company
Gowling Lafleur Henderson Llp
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