Composition and dosage form for sustained effect of levodopa

Details Composition and dosage form for sustained effect of levodopa Composition and dosage form for sustained effect of levodopa

A - Human Necessities

61

K

A61K 31/4458 (2006.01) A61K 31/15 (2006.01) A61K 31/195 (2006.01) A61P 25/16 (2006.01)

Patent

CA 2553156

The present invention encompasses compositions for the treatment of Parkinson~s disease comprising a therapeutically effective amount of levodopa or a metabolic precursor thereof and at least one dopamine transport inhibitor in sufficient amount to decrease dopamine degradation, wherein the dopamine transport inhibitor is administered to avid dyskinesia.

L'invention concerne des compositions utilisées dans le traitement de la maladie de Parkinson comprenant une quantité thérapeutiquement efficace de levodopa ou d'un précurseur métabolique et au moins un inhibiteur de transport de la dopamine en quantité suffisante, ce qui permet de diminuer la dégradation de la dopamine, l'inhibiteur de transport de la dopamine étant administré de manière à éviter la dyskinésie.

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