Composition and drug delivery of bisphosphonates

A - Human Necessities – 61 – K

Patent

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A61K 31/675 (2006.01) A61K 9/22 (2006.01) A61K 47/12 (2006.01) A61P 19/00 (2006.01) A61P 35/00 (2006.01) A61P 37/00 (2006.01)

Patent

CA 2751854

The present invention provides methods of treating or preventing a medical condition that is responsive to a bisphosphonate compound in a subject. The methods comprise administering to the subject a pharmaceutical composition comprising a therapeutically effective amount of the bisphosphonate no less frequently than a bi-weekly dosage schedule. In some embodiment, the bisphosphonate compound is zoledronic acid.

La présente invention concerne des procédés de traitement ou de prévention d'une affection médicale répondant favorablement à un composé de type bisphosphonate chez un sujet. Ces procédés comprennent l'administration audit sujet d'une composition pharmaceutique comprenant une quantité thérapeutiquement efficace de bisphosphonate selon un schéma posologique au moins bihebdomadaire. Dans certains modes de réalisation, ce composé de type bisphosphonate est l'acide zolédronique.

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