Composition and its use for treating neuropathic sensory loss

A - Human Necessities – 61 – K

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Details

A61K 31/165 (2006.01) A61K 31/245 (2006.01) A61K 31/445 (2006.01) A61P 23/00 (2006.01) A61P 25/02 (2006.01)

Patent

CA 2507217

The present invention relates to methods of reducing the effects of neuropathically induced negative sensory phenomena (NSP). NSP are manifested as the decreased ability to feel light touch, pain, proprioception, vibration, warm/heat, and coolness/cold. The NSP are treated by application of an anesthetic. The anesthetic is preferably a benzoic acid-based anesthetic. Specifically, a patch containing about 5% lidocaine may be used. The anesthetic is transdermally administered to a patient suffering from NSP at or near the locus of the negative sensory phenomena.

La présente invention concerne des méthodes propres à réduire des phénomènes sensoriels négatifs d'origine névropathique. Ces phénomènes se manifestent par une difficulté à percevoir un toucher léger, une douleur, des vibrations, la chaleur plus ou moins forte et le froid plus ou moins marqué, ainsi qu'une perte de proprioception. Le traitement fait intervenir un anesthésique, de préférence à base d'acide benzoïque. Spécifiquement, on peut utiliser un timbre renfermant quelque 5 % de lidocaïne. L'anesthésique est administré transdermiquement au patient au point ou à proximité des phénomènes sensoriels négatifs.

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