C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/475 (2006.01) A61K 38/18 (2006.01) A61L 27/34 (2006.01) A61L 27/54 (2006.01) A61P 19/08 (2006.01) C07K 14/51 (2006.01)
Patent
CA 2692240
A composition comprising a synthetic growth factor analogue comprising a non- growth factor heparin binding region, a linker and a sequence that binds specifically to a cell surface receptor and an osteoconductive material where the synthetic growth factor analogue is attached to and can be released from the osteoconductive material and is an amplifier/co-activator of osteoinduction.
L'invention concerne une composition comprenant un facteur de croissance synthétique analogue comprenant une zone de liaison d'héparine à facteur de non croissance, un élément de liaison et une séquence se liant spécifiquement à un récepteur de la surface cellulaire et un matériau ostéoconducteur. Dans l'invention, le facteur de croissance synthétique analogue est attaché au matériau ostéoconducteur et peut être libéré de celui-ci, et est un amplificateur/co-activateur de l'ostéoinduction.
Atkinson Brent Lee
Zamora Paul
Bergstein Corey
Biosurface Engineering Technologies Inc.
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