Composition and method for enhancing transdermal...

A - Human Necessities – 61 – K

Patent

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A61K 9/00 (2006.01) A61N 1/30 (2006.01)

Patent

CA 2190370

A composition comprises an agent to be delivered through a body surface and an electrotransport enhancer having a hydrophobic tail and a polar head of specific characteristics. An electrotransport delivery device (10) is also provided having a reservoir (16) comprising the agent to be delivered and the electrotransport enhancer of the invention. The electrotransport enhancers increase the electrotransport delivery rate of the agent through the surface while reducing the electrical resistance of the surface during electrotransport of the agent.

Composition comprenant une substance devant être administrée par voie percutanée et un accélérateur d'électrotransport présentant une queue hydrophobe et une tête polaire ayant des caractéristiques spécifiques. Le dispositif d'administration par électrotransport (10) est muni d'un réservoir (16) contenant la substance à administrer et l'accélérateur. Les accélérateurs d'électrotransport accroissent la vitesse de passage de substances à travers la surface tout en réduisant la résistance superficielle pendant l'électrotransport desdites substances.

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