A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/00 (2006.01) A61K 31/34 (2006.01) A61K 31/355 (2006.01) A61K 38/39 (2006.01)
Patent
CA 2378760
The healing of wounds is enhanced by contacting the wound surfaces with a dressing of D-glucose polysaccharide obtained by hydrolysis of starch containing ascorbic acid, collagen type I and alpha-tocopherol acetate. The collagen type I, and the ascorbic acid in the dressing are the typical chemotactic agents of neutrophils, fibroblasts and/or endothelial cells. These combinations can be present in the dressing as a gel. The composition material can be applied to the wound as a particulate material such as a powder, or as material such as a gel, paste, dispersion, solution or syrup. Wounds, in particular those occurring in the skin as second and third degree burns, stasis ulcers, trophic lesions, such as decubitus ulcers, severe cuts and abrasions which are commonly resistant to the natural healing process, may be treated with this composition. The application of this combination to open wounds greatly accelerates the rate of healing and reduces scarring. The invention includes an article useful in the therapy for surface wounds comprising the suspension of particles on non-adherent gauze and a bandage tape.
Il est possible d'accélérer la cicatrisation de plaies en appliquant à leur surface un pansement d'un polysaccharide de glucose obtenu par hydrolyse d'amidon contenant en outre de l'acide ascorbique, du collagène de type I et de l'acétate d'alpha-tocophérol. Le collagène de type I, et l'acide ascorbique du pansement sont des agents chimiotactiques types des neutrophiles, des fibroblastes et/ou des cellules endothéliales. Cette combinaison peut se présenter sous la forme d'un gel ou d'un matériau particulaire en poudre, en gel, en pâte, en dispersion, en solution ou en sirop. Les plaies, et en particulier celles résultant de brûlures au deuxième et au troisième degré, les ulcères de stase, et les lésions trophiques, telles que les ulcères de décubitus, les coupures profondes, et les abrasions, normalement peu susceptibles de guérison spontanée, peuvent se traiter à l'aide de ladite composition dont l'application sur des plaies ouvertes accélère notablement la guérison tout en réduisant les marques de cicatrisation. L'invention porte également sur un article de traitement des plaies superficielles consistant en une suspension de particules imprégnant une gaze non adhérente et un ruban de bandage.
Deroyal Industries Inc.
Mccarthy Tetrault Llp
Obi-Tabot Eliot T.
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