C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/55 (2006.01) A61K 38/46 (2006.01) A61K 39/00 (2006.01) C12N 9/16 (2006.01) C12N 15/86 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2286477
Disclosed are a novel prostatic acid phosphatase and corresponding coding region derived from mouse. Also disclosed is a method of producing an immune response against an autologous polypeptide tumor antigen by immunizing a subject with a xenogeneic polypeptide antigen, either alone, as part of a viral antigen construct, or as part of a pulsed dendritic cell preparation.
L'invention a trait à une nouvelle phosphatase acide prostatique issue de la souris, et à la région codante correspondante. Elle concerne également une méthode permettant de provoquer une réaction immunitaire contre un antigène tumoral de polypeptide autologue par immunisation du sujet à l'aide d'un antigène de polypeptide hétérologue, que ce soit isolément, dans le cadre d'un produit de recombinaison d'antigène viral, ou dans le cadre d'une préparation de cellule dendritique activée.
Laus Reiner
Ruegg Curtis L.
Shapero Michael H.
Yang Demao
Dendreon Corporation
Gowling Lafleur Henderson Llp
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