Composition and method for inhibiting lipogenesis in mammals

A - Human Necessities – 61 – K

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A61K 31/00 (2006.01) A23B 4/14 (2006.01) A61K 31/16 (2006.01) A61K 31/19 (2006.01) A61K 31/22 (2006.01) A61K 31/275 (2006.01)

Patent

CA 1142088

ABSTRACT This invention relates to a composition for inhibiting lipogenesis in animals intended for human consumption after slaughter. There is provided a composition suitable for use in inhibition of lipogenesis in animals intended for human consumption after slaughter comprising a cyclopropane carboxylic acid derivative of formula Image (I) wherein R is C4 - C16 alkyl, acetoxymethyl or phenyl, one of R1 and R2 is hydrogen, the other of R1 and R2 being hydrogen or -CN, and R3 is -OH, -NH2 or -OR4, wherein R4 is C1 - C4 alkyl, in association with a pharmaceutically or veterinarily acceptable carrier therefor, and the use of derivatives of formula I in inhibiting lipogenesis. It has been found that compounds of formula I have lipogenesis inhibiting activity in animals intended for human consumption after slaughter, especially, for example, in pigs, thereby providing leaner meat after slaughter.

344422

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