Composition and method for parenteral administration of...

A - Human Necessities – 61 – K

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A61K 31/19 (2006.01) A61K 9/08 (2006.01) A61K 31/192 (2006.01) A61K 31/195 (2006.01) A61K 47/18 (2006.01) A61P 29/00 (2006.01)

Patent

CA 2361160

Pharmaceutical compositions are disclosed suitable for parenteral administration having anti-inflammatory, analgesic, and anti-pyretic properties, which consist of a therapeutically effective amount of d,l or 1-lysine salt of R,S or S-ibuprofen as active ingredient dissolved in sterile water to form a solution in the absence of an inert atmosphere and either substantially free or absolutely free of any excipient, organic solvent, buffer, acid, base, salt other than the active ingredient and capable of storage in the absence of an inert atmosphere. Also disclosed are methods employing the new compositions in the treatment of pain and inflammation, in reducing fever and in treating patent ductus arterious or intraventricular hemorrhage in prematurely born neonates.

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