A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/395 (2006.01) C07K 16/00 (2006.01) C12Q 1/02 (2006.01) G01N 33/53 (2006.01) G01N 33/68 (2006.01) A61K 38/00 (2006.01) A61K 39/00 (2006.01)
Patent
CA 2183566
Inflammation can be treated or prevented altogether by administering a preparation comprising IgA. These preparations also can effect immunomodulation. Preferably, the preparation includes multimeric IgA and is essentially free of IgG in its various forms. Other compounds, such as antibiotics, antiphlogistic agents and antacids, also may be administered. Immunoglobulin A may also be used in vaccines to prevent inflammation. Additionally, an improved assay for evaluating anti-inflammatory activity is provided.
Selon l'invention, on peut traiter ou prévenir tout à fait les inflammations en administrant une préparation comprenant une IgA. Ces préparations peuvent également avoir un effet immunomodulateur. De préférence, la préparation comprend une IgA multimère et ne contient essentiellement pas d'IgC sous ses diverses formes. On peut également administrer d'autres composés, tels que des antibiotiques, des agents antiphlogistiques ainsi que des antiacides. De même, on peut utiliser l'immunoglobuline A dans des vaccins afin de prévenir l'inflammation. En outre, l'invention se rapporte à un dosage amélioré destiné à évaluer l'activité anti-inflammatoire.
Eibl Martha
Leibl Heinz
Linnau Yendra
Mannhalter Josef W.
Wolf Herrmann
Immuno Aktiengesellschaft
Smart & Biggar
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