Composition and method for producing superovulation in cattle

C - Chemistry – Metallurgy – 07 – K

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167/103.44

C07K 14/59 (2006.01) A61K 47/10 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1311413

ABSTRACT OF THE DISCLOSURE A hormone composition is provided herein for producing superovulation in mammals, e.g., cattle, goats, swine, sheep, horses, exotic mammals or humans. The composition has a particu- lar ratio of follicle stimulating hormone (FSH) and luteinizing hormone (LH) which produces an optimum ovulation response in mammals and promotes out of season breeding and twinning. The composition can be produced from mammal pituitary glands or by recombinant DNA procedures and can, in a preferred embodiment, be preserved in a phosphate buffered saline solution of thymol.

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