Composition and method for promoting oral health

Details Composition and method for promoting oral health Composition and method for promoting oral health

A - Human Necessities

61

K

A61K 31/7016 (2006.01) A61K 9/20 (2006.01) A61K 31/375 (2006.01)

Patent

CA 2405099

The present invention relates to a method for increasing unstimulated whole saliva in a patient. The method comprises orally administering an effective amount of a disaccharide, such as maltose, trehalose, or anhydrous crystalline maltose, to the patient in a dosage form such as a lozenge. The disaccharide can also be administered in combination with an effective amount of vitamin C, or a derivative thereof, such as a vitamin C ester. The invention is also directed to a pharmaceutical composition comprising a disaccharide in combination with vitamin C, or a derivative thereof, such as a vitamin C ester. The method is used to treat diseases such as Sjögren's syndrome and xerostomia.

La présente invention concerne une méthode qui augmente la salive entière non stimulée chez un patient. La méthode consiste à administrer au patient, par voie orale, une quantité effective d'un disaccharide, tel qu'un maltose, un tréhalose, ou un maltose cristallin anhydre, dans une forme posologique en pastille. Le disaccharide peut être également administré en association avec une quantité effective de vitamine C, ou d'un dérivé de la vitamine C (tel qu'un ester de vitamine C). L'invention concerne en outre une composition pharmaceutique contenant un disaccharide associé à la vitamine C, ou à un dérivé de la vitamine C (tel qu'un ester de vitamine C). Cette méthode est mise en oeuvre pour traiter des maladies telles que le syndrome de Sjögren ou la xérostomie.

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