A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/28 (2006.01) A61K 31/295 (2006.01) A61K 31/30 (2006.01) A61K 31/315 (2006.01) A61K 33/04 (2006.01)
Patent
CA 2124204
2124204 9310777 PCTABS00022 A method for reducing free radical cellular oxidative stress in warm-blooded animals showing symptoms of free radical toxicity is disclosed. The method comprises the steps of confirming the presence of a free radical cellular oxidative stress in the animal; determining which trace minerals selected from the group consisting of copper, zinc, iron and manganese, with or without optional amounts of selenium are needed to strengthen and maintain the functioning of enzymes which relate to oxidative bursts in neutrophils and macrophages in the animal; providing a composition containing effective amounts of at least one of the minerals copper, zinc, iron and manganese in the form of an amino acid chelate having a ligand to mineral ratio of at least 1:1, a molecular weight of no more than 1500 daltons and a stability constant of between about 106 and 1016, with or without optional amounts of selenium which may be present either in amino acid chelated form or as inorganic selenium, and administering the composition to the animal, preferably in oral form. The presence of free radical cellular oxidative stress is preferably confirmed by direct assay of the activity of oxidative enzymes selected from the group consisting of CuZnSOD, glutathione peroxidase and catalase.
Ashmead H. Dewayne
Ashmead Harvey H.
Jeppsen Robert B.
Albion International Inc.
Smart & Biggar
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