Composition and method for regulating the adhesion of cells...

Details Composition and method for regulating the adhesion of cells... Composition and method for regulating the adhesion of cells...

C - Chemistry, Metallurgy

07

K

C07K 17/08 (2006.01) A61K 38/00 (2006.01) A61K 38/18 (2006.01) A61K 38/39 (2006.01) C07K 1/10 (2006.01) C07K 1/107 (2006.01) C08G 65/32 (2006.01) C12N 5/00 (2006.01) C12N 7/02 (2006.01)

Patent

CA 2277995

The present invention is directed to a composition and method for regulating the adhesion of cells and biomolecules to hydrophobic surfaces and hydrophobic coated surfaces. The composition is an biomolecule conjugated end-group activated polymer (EGAP). The biomolecule conjugated EGAP can be put to numerous using including cell adhesion, cell growth, cell sorting and other biological assays.

Cette invention concerne une composition et un procédé permettant de réguler l'adhérence de cellules et de biomolécules à des surfaces hydrophobes ou à des surfaces possédant un revêtement hydrophobe. Cette composition consiste en un polymère qui est activé au niveau du groupe terminal (PAGT) et qui est conjugué à une biomolécule. Ce PAGT conjugué à une biomolécule peut être utilisé dans de nombreuses applications comme, par exemple, dans des analyses d'adhérence cellulaire, de croissance cellulaire, de tri des cellules ou autres analyses biologiques.

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