Composition and method for stable injectable liquids

Details Composition and method for stable injectable liquids Composition and method for stable injectable liquids

A - Human Necessities

61

K

A61K 9/16 (2006.01) A61K 9/00 (2006.01) A61K 9/10 (2006.01)

Patent

CA 2424656

A composition for delivering a stable, bioactive compound to a subject comprising a first component and a second component, the first component comprises microparticles of sugar glass or a phosphate glass containing the bioactive agent. The sugar glass or phosphate glass optionally includes a glass formation facilitator compound, and the second component comprises at least one biocompatible liquid perfluorocarbon in which the first component is insoluble and dispersed. The liquid perfluorocarbon optionally includes a surfactant.

L'invention concerne une composition destinée à administrer un composé stable et bioactif à un sujet et comportant un premier et un second composant, le premier composant contenant des microparticules d'un verre de glucide ou un verre de phosphate contenant l'agent bioactif. Le verre de glucide ou de phosphate peut comporter un composé facilitant la formation du verre, et le second composant comporte au moins un perfluorocarbone liquide biocompatible, dans lequel le premier composant est insoluble et dispersé. Le perfluocarbone peut comporter un tensio-actif.

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