A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/35 (2006.01) A61K 38/42 (2006.01) A61K 39/385 (2006.01) A61P 37/08 (2006.01) A61K 38/11 (2006.01)
Patent
CA 2402636
The present invention is related to a method for modulating the immune system of a mammal patient towards an allergen, which comprises the step of inducing a pre-sensitisation of the immune system of said patient towards an immunogen carrying at least one T cell epitope homologous and functionally similar to an epitope present on said allergen and deriving from a naturally-occurring antigen in order to modify the response of said patient to a further sensitisation to said allergen, allowing that the immune response towards the allergen is modulated and that no allergy towards said allergen will be developed in said patient.
L'invention porte sur un procédé modulant le système immunitaire d'un mammifère vis-à-vis d'un allergène consistant à induire une présensibilisation du système immunitaire du patient vis-à-vis d'un allergène portant au moins un épitope de cellule T homologue et fonctionnellement similaire à un épitope présent dans ledit allergène, et dérivant d'un antigène produit naturellement, afin de modifier la réponse du patient à une nouvelle sensibilisation par ledit allergène. La réponse immunitaire vis-à-vis de l'allergène étant ainsi modulée, le patient ne développera pas d'allergie vis-à-vis dudit allergène.
Jacquemin Marc
Saint-Remy Jean-Marie
Collen Research Foundation
Gowling Lafleur Henderson Llp
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