Composition and method for topical application to skin, hair...

Details Composition and method for topical application to skin, hair... Composition and method for topical application to skin, hair...

A - Human Necessities

61

K

A61K 8/68 (2006.01)

Patent

CA 2231119

A composition and method thereof treating or conditioning human skin, hair or nails is described. The composition is topically applied in an effective amount and contains from about 0.0001 to about 50 wt. % of a ceramide derivative containingsphingoid bases having amide, but not ester linkages to a 2 (alpha)-hydroxy carboxylic acid and a safe and effective amount of a pharmaceutical or cosmetically acceptable carrier. The composition effectively treats or conditions areas of fine flakes having histogram values of 10 to 128. Treated areas exhibit a desquamation value difference of 1.0 or greater at day 28 after treatment commences compared to a desquamationvalue of untreated areas.

Divulgation d'une composition et description d'une méthode de traitement ou de conditionnement de la peau, des cheveux ou des ongles humains avec cette composition. La composition est constituée d'environ 0,0001 à environ 50 % en poids d'un dérivé de céramide contenant des bases sphingoïdes ayant des liaisons amide, mais non des liaisons ester, avec un acide 2 (alpha)-hydroxycarboxylique et d'une quantité sûre et efficace d'un vecteur acceptable sur le plan pharmaceutique ou cosmétique. Appliquée localement en une quantité efficace, elle traite ou conditionne efficacement les zones de fines squames ayant des valeurs d'histogramme de 10 à 128. Les endroits traités affichent une différence dans la valeur de la desquamation de 1,0 ou plus au jour 28 après le début du traitement comparativement à une valeur de desquamation des endroits non traités.

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