Composition and method for treating chronic allograft rejection

Details Composition and method for treating chronic allograft rejection Composition and method for treating chronic allograft rejection

A - Human Necessities

61

K

A61K 38/13 (2006.01) A61K 31/7076 (2006.01) A61P 37/06 (2006.01)

Patent

CA 2465120

The invention provides a composition and a method for preventing or ameliorating the causes of chronic allograft rejection of a donor organ by a transplant recipient. The method includes concomitant administration to the allograft recipient of therapeutically effective amounts of cyclosporin and 2- chlorodeoxyadenosine. The composition comprises a combination of cyclosporin and 2-chlorodeoxyadenosine in therapeutically effective amounts suitable for the practice of the method.

L'invention concerne une composition et une méthode de prévention ou d'amélioration des causes du rejet de greffe allogénique chronique d'un organe d'un donneur par un receveur de greffe. La méthode consiste à administrer de manière simultanée des quantités thérapeutiquement efficaces de cyclosporine et de 2-chlorodésoxyadénosine au receveur de greffe allogénique. La composition comprend une combinaison de cyclosporine et de 2-chlorodésoxyadénosine en quantités thérapeutiquement efficaces pour mettre en oeuvre ladite méthode.

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