Composition and method for treating cystic fibrosis

A - Human Necessities – 61 – K

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A61K 48/00 (2006.01) A61K 9/12 (2006.01) A61K 9/127 (2006.01) A61K 9/72 (2006.01) A61K 31/70 (2006.01) A61K 38/17 (2006.01) A61K 38/46 (2006.01) A61K 47/48 (2006.01) C07K 14/47 (2006.01)

Patent

CA 2115364

2115364 9303709 PCTABS00020 Disclosed is a pharmaceutical composition suitable for the pulmonary administration of therapeutically effective amounts of DNase, a macromolecule operatively coding for a functional protein to remedy the cellular defect associated with cystic fibrosis and sufficient lipid to form cationic complexes with the macromolecule, effective to deliver the macromolecule into pulmonary cells in vivo). Additionally disclosed are methods for the treatment of cystic fibrosis.

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