A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/48 (2006.01) A01L 15/00 (2006.01) A61K 9/70 (2006.01) A61K 31/4418 (2006.01) A61K 47/10 (2006.01) A61K 47/46 (2006.01)
Patent
CA 2231769
A nail-permeable medication means is disclosed for delivering a medicament through nails, claws, hoofs, or other similar hardened tissue of dermal derivation. The nail-permeable medication means includes a proteolytic enzyme component which facilitates permeation of substances through the hardened nail or keratin tissue, and also includes a medicament component selected to treat a specific disease. The nail-permeable medication means is particularly useful for treating onychomycosis of the fingernail or toenail, and avoids the need for more drastic therapeutic modalities, such as removal of the nail.
L'invention concerne une forme médicamenteuse, capable de traverser les ongles et de faire passer un médicament à travers les ongles, les griffes, les sabots ou d'autres tissus similaires, formés par durcissement du derme. La forme médicamenteuse capable de traverser les ongles comprend une enzyme protéolytique qui facilite la perméation de la substance à travers l'ongle dur ou le tissu kératineux. L'invention concerne également une forme médicamenteuse capable de traiter une maladie spécifique. La forme médicamenteuse capable de traverser l'ongle est particulièrement utile pour traiter l'onychomycose des ongles des doigts ou des orteils, ce qui évite d'avoir à prendre des mesures thérapeutiques plus draconiennes, comme l'excision de l'ongle.
Petersen Robert V.
Sorenson James L.
Oyen Wiggs Green & Mutala Llp
Sorenson Pharmaceutical Inc.
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