A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/4418 (2006.01) A61K 31/196 (2006.01) A61K 31/198 (2006.01) A61K 45/06 (2006.01)
Patent
CA 2741954
The present invention relates, in general, to fibroproliferative disorders, and, in particular, to a method of treating, preventing or reducing fibroproliferative disorders by administering to a mammal in need a composition comprising pharmacologically effective doses of a cytokine modifier, such as tranilast or pirfenidone, and an anti-oxidant which is a precursor of glutathione, such as N-acetyl-cysteine, or their pharmaceutically acceptable derivatives, salts, metabolites, or structural or functional analogues thereof.
La présente invention porte, d'une manière générale, sur des troubles à prolifération fibreuse et, en particulier, sur un procédé de traitement, de prévention et de réduction de troubles à prolifération fibreuse par administration à un mammifère le nécessitant d'une composition comprenant des doses pharmacologiquement efficaces d'un modificateur de cytokine, tel que le tranilaste ou la pirfénidone, et un anti-oxydant qui est un précurseur du glutathion, tel que la N-acétyl-cystéine, ou leurs dérivés, sels, métabolites ou analogues structuraux ou fonctionnels pharmaceutiquement acceptables.
Maksumova Lola
Unwin Douglas Harry
Oyen Wiggs Green & Mutala Llp
Pacific Therapeutics Ltd.
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