Composition and method for treating lupus nephritis

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/12 (2006.01) A61K 38/17 (2006.01) A61K 39/395 (2006.01) A61P 37/02 (2006.01) C07H 21/04 (2006.01) C07K 5/00 (2006.01) C07K 14/00 (2006.01) C07K 14/46 (2006.01) C07K 14/705 (2006.01) C07K 16/18 (2006.01) C07K 19/00 (2006.01) C12N 1/19 (2006.01) C12N 1/21 (2006.01) C12N 15/11 (2006.01) C12N 15/85 (2006.01) C12N 15/86 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) G01N 33/566 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2504561

The present invention provides novel isolated BFLP1698 polynucleotides and polypeptides encoded by the BFLP1698 polynucleotides. Also provided are the antibodies that immunospecifically bind to a BFLP1698 polypeptide or any derivative (including fusion derivative), variant, mutant, or fragment of the BFLP1698 polypeptide, polynucleotide or antibody. The invention additionally provides methods in which the BFLP1968 polypeptide, polynucleotide and antibody are utilized in the detection and treatment of a broad range of pathological states, as well as to other uses.

L'invention concerne de nouveaux polynucléotides isolés BFLP1698 et des polypeptides codés par les polynucléotides BFLP1698. La présente invention porte également sur les anticorps qui se lient de manière immunospécifique à un polypeptide BFLP1698 ou à un dérivé quelconque de celui-ci (y compris des dérivés de fusion), à une variante, un mutant ou un fragment du polypeptide BFLP1698, du polynucléotide BFLP1698 ou d'un anticorps. Cette invention concerne aussi des méthodes selon lesquelles le polypeptide BFLP1698, le polynucléotide BFLP1698 ou l'anticorps sont utiles à la détection et au traitement d'une large palette d'états pathologiques, ainsi que dans d'autres applications.

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