Composition and method for treating lupus nephritis

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/12 (2006.01) A61K 38/17 (2006.01) A61P 13/12 (2006.01) A61P 37/00 (2006.01) C07K 14/47 (2006.01) C07K 14/705 (2006.01) C07K 16/18 (2006.01) C07K 19/00 (2006.01) C12N 15/63 (2006.01) C12P 21/02 (2006.01) C12P 21/08 (2006.01) C12Q 1/68 (2006.01) G01N 33/566 (2006.01) A61K 31/436 (2006.01)

Patent

CA 2506633

The present invention provides novel isolated BFLP0169 polynucleotides and polypeptides encoded by the BFLP0169 polynucleotides. Also provided are the antibodies that immunospecifically bind to a BFLP0 169 polypeptide or any derivative (including fusion derivative), variant, mutant or fragment of the BFLP0169 polypeptide, polynucleotide or antibody. The invention additionally provides methods in which the BFLP0169 polypeptide, polynucleotide and antibody are utilized in the detection and treatment of a broad range of pathological states, as well as to other uses.

La présente invention concerne de nouveaux polynucléotides BFLP0169 isolés, et des polypeptides codés par les polynucléotides BFLP0169. Elle concerne également des anticorps qui se lient de manière immunospécifique à un polypeptide BFLP0169 ou à un dérivé (y compris un dérivé hybride), variant, mutant ou fragment quelconque du polypeptide, polynucléotide ou anticorps BFLP0169. L'invention concerne en outre des méthodes dans lesquelles les polypeptide, polynucléotide et anticorps BFLP0169 sont utilisés pour la détection et le traitement d'un large éventail d'états pathologiques, ainsi que pour d'autres usages.

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