A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/517 (2006.01) A61P 21/00 (2006.01) C07D 401/06 (2006.01)
Patent
CA 2711743
A compound in combination with a pharmaceutically acceptable carrier, the compound having a formula: wherein: R1 is a member of the group consisting of hydrogen, halogen, nitro, benzo, lower alkyl, phenyl, and lower alkoxy; R2 is a member of the group consisting of hydroxy, acetoxy, and lower alkoxy; and R3 is a member of the group consisting of hydrogen and lower alkenoxy-carbonyl; and n is either 1 or 2; and pharmaceutically acceptable salts thereof; for use in treatment of or prevention of skeletal muscle fibrosis and/or for inducing skeletal muscle regeneration.
L'invention porte sur un composé combiné à un support pharmaceutiquement acceptable. Le composé a une formule dans laquelle : R1 est un élément du groupe constitué par hydrogène, halogène, nitro, benzo, alkyle inférieur, phényle et alcoxy inférieur ; R2 est un élément du groupe constitué par hydroxy, acétoxy et alcoxy inférieur ; R3 est un élément du groupe constitué par hydrogène et alcénoxy-carbonyle inférieur ; et n est soit 1, soit 2 ; et les sels pharmaceutiquement acceptables dudit composé pour utilisation dans le traitement ou la prévention d'une fibrose des muscles squelettiques et/ou pour induire une régénérescence des muscles squelettiques.
Nagler Arnon
Pines Mark
Agricultural Research Organization
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Hadasit Medical Research Services And Development Company Ltd.
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