Composition and method for treatment of cmv infections

Details Composition and method for treatment of cmv infections Composition and method for treatment of cmv infections

C - Chemistry, Metallurgy

07

H

C07H 21/04 (2006.01) A61K 48/00 (2006.01) C07H 21/00 (2006.01) C12N 15/11 (2006.01) C12Q 1/68 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2285921

This invention concerns compositions and methods for the treatment of CMV infections. Antisense oligonucleotides are provided which are effective antiviral agents. In preferred embodiments, the oligonucleotides contain at least one 2'-methoxyethoxy modification and may be chimeric oiigonucleotides.

L'invention concerne des compositions et des procédés pour le traitement des infections par le cytomégalovirus. On décrit des oligonucléotides antisens qui sont des agents anitviraux efficaces. Dans des modes de réalisation préférés, les oligonucléotides présentent au moins une modification 2'-méthoxyéthoxy et peuvent être des oligonucléotides chimères.

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