Composition and method for treatment of mrsa

A - Human Necessities – 61 – K

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A61K 31/155 (2006.01) A61K 41/00 (2006.01) A61P 31/00 (2006.01)

Patent

CA 2732307

The present invention provides a photosensitizing composition for treatment of MRSA comprising a photosensitizer and chlorhexidine and a pharmaceutically acceptable carrier. The present invention also provides a method for reducing disease causing microbes comprising: applying the composition comprising a photo sensitizer, chlorhexidine at a concentration of more than about 0.01% and less than about 2% v/v, and a pharmaceutically acceptable carrier to a treatment site; and applying light to the treatment site at a wavelength absorbed by the photosensitizer so as to reduce the microbes at the treatment site.

La présente invention concerne une composition photosensibilisante pour le traitement des SDRM contenant un agent photosensibilisant et de la chlorhexidine et un véhicule pharmaceutiquement acceptable. La présente invention concerne également une méthode permettant de réduire les microbes responsables d'une maladie consistant à : appliquer la composition contenant un agent photosensibilisant, de la chlorhexidine à une concentration comprise entre environ 0,01 % et environ 2 % v/v, et un véhicule pharmaceutiquement acceptable sur un site de traitement ; et appliquer une lumière sur le site de traitement à une longueur d'onde absorbée par l'agent photosensibilisant de façon à réduire les microbes au niveau du site de traitement.

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