Composition and method for use of pyridinium derivatives in...

A - Human Necessities – 61 – K

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A61K 31/4427 (2006.01) A61K 31/44 (2006.01) A61K 31/4425 (2006.01) A61P 1/16 (2006.01) A61P 3/10 (2006.01) A61P 9/00 (2006.01) A61P 11/00 (2006.01) A61P 13/12 (2006.01) A61P 17/00 (2006.01) A61P 17/02 (2006.01) A61P 17/04 (2006.01) A61P 17/06 (2006.01) A61P 17/08 (2006.01) A61P 17/10 (2006.01) A61P 25/28 (2006.01) A61P 27/02 (2006.01) A61P 31/18 (2006.01) A61P 35/00 (2006.01) C07D 213/60 (2006.01) C07D 409/06 (2006.01) C07D 409/14 (2006.01) C07D 417/12 (2006.01)

Patent

CA 2361863

The invention discloses a new class of compounds particularly pyridinium derivatives, which have been found to exhibit triple function of a free radical scavenger (antioxidant), AGE breaker and AGE inhibitor, and cosmetic composition comprising these compounds contained in a cosmetically acceptable carrier. The invention also discloses a method of cosmetic application by applying such composition. The invention further discloses a pharmaceutical composition, comprising said compounds useful in scavenging free radicals from the body cells of a mammal, a method of scavenging free radicals from the body cells of a mammal and a method of treating of diseases caused by accumulation of free radicals in the body cells of a mammal by administering a composition made with the compounds of the invention. The invention in addition, also discloses composition and method for inhibiting AGE in a mammal by use of the compounds of the same group.

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