G - Physics – 01 – N
Patent
G - Physics
01
N
150/3, 150/9
G01N 33/68 (2006.01) G01N 33/52 (2006.01)
Patent
CA 1333251
A new and improved method and composi- tion for determining the presence and concentra- tion of low to trace amounts of proteins, such as albumin, in a test sample, such as urine. The method includes using a reagent composition capable of interacting with low to trace amounts of proteins to produce a visually or instrument- ally detectable and/or measurable response. The method can be used in wet assays or in dry test strip assays, wherein the reagent composition is incorporating into a carrier matrix. The new and improved reagent composition, comprising a dye, such as a polyhydroxybenzenesulfonephthalein- type indicator, like pyrocatechol violet; a tung- state, such as ammonium tungstate; and, if neces- sary, a suitable buffer, is incorporated into the carrier matrix to provide sufficient sensi- tivity to low to trace protein levels and suffi- cient color resolution between low to trace pro- tein levels, thereby affording an accurate and trustworthy protein assay of test samples having a low protein concentration.
600070
Miles Inc.
Osler Hoskin & Harcourt Llp
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