A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/53 (2006.01) A61K 31/21 (2006.01) A61K 31/35 (2006.01) A61K 31/40 (2006.01) A61K 31/44 (2006.01) A61K 31/495 (2006.01) A61K 31/497 (2006.01)
Patent
CA 2563693
A method of decreasing renal ischemic damage comprising a) identifying an organism having a kidney that is susceptible to renal ischemic damage from an ischemic event; and b) administering to the organism one or more than one effective dose of an agent prior to the ischemic event; where administering to the organism the one or more than one effective dose of the agent serves to at least partially protect the organism's kidney from damage during a subsequent ischemic event. A composition for decreasing renal ischemic damage comprising one or more than one phosphodiesterase inhibitor, and one or more than one HMG- CoA reductase inhibitor.
L'invention concerne un procédé de réduction de dommages ischémiques rénaux consistant a) à identifier un organisme dont un rein est exposé à des dommages ischémiques dus à un événement ischémique, et b) à administrer à l'organisme une ou plusieurs doses efficaces d'un agent avant l'événement ischémique, de manière à protéger au moins partiellement le rein contre des dommages ischémiques dus à un événement ischémique consécutif. L'invention concerne également une composition de réduction de dommages ischémiques rénaux contenant un ou plusieurs inhibiteurs de phosphodiestérase, et un ou plusieurs inhibiteurs de HMG-CoA réductase.
Gowling Lafleur Henderson Llp
Loma Linda University
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