Composition and method of treating depigmentation disorders

A - Human Necessities – 61 – K

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A61K 33/24 (2006.01) A61K 33/26 (2006.01) A61K 33/32 (2006.01) A61K 33/34 (2006.01) A61N 5/06 (2006.01)

Patent

CA 2102514

2102514 9220354 PCTABS00017 Vitiligo and other tyrosinase-positive depigmentation disorders are treated by topical application of a pseudocatalase and subsequent exposure to a sub-minimal erythema dose of UVB light. After a course of treatment, pigmentation of the affected areas can be maintained by treatment with the pseudocatalase without UVB light treatment. The preferred pseudocatalases are transition metal co-ordination complexes, especially manganese (II) bicarbonate.

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