Composition and methods for administration of...

A - Human Necessities – 61 – K

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A61K 31/337 (2006.01) A61K 9/127 (2006.01) A61L 31/16 (2006.01) A61P 9/10 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2358638

(57) Abstract: A composition for administration of a paclitaxel derivative is described. The composition includes a paclitaxel derivative having a water solubility less than that of paclitaxel and a suitable carrier. A polymer composition for administration of the poorly water-soluble paclitaxel derivative is also described. Method for treating restenosis are also described.

La présente invention concerne une composition permettant l'administration d'un dérivé de paclitaxel. Ladite composition comprend un dérivé de paclitaxel dont la solubilité dans l'eau est inférieure à celle du paclitaxel, et un excipient adéquat. L'invention concerne également une composition polymère permettant l'administration du dérivé de paclitaxel peu soluble dans l'eau, ainsi que des procédés de traitement de la resténose.

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