Composition and methods for the production of biological...

A - Human Necessities – 61 – L

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A61L 27/38 (2006.01) C12N 5/071 (2010.01) C12N 5/077 (2010.01) A61K 35/12 (2006.01) A61K 35/32 (2006.01) A61L 27/24 (2006.01) A61L 27/56 (2006.01) A61L 27/58 (2006.01) A61F 2/00 (2006.01)

Patent

CA 2441994

The present invention relates to compositions and methods for preparing tissues or tissue constructs. In selected embodiments, the invention relates to the construction of a multi-layered biological structure (i.e. system) that includes a cellular support matrix seeded with living cells derived from a native tissue. The present invention also relates to tissue culture protocols to promote the in vitro growth of tissues and tissue constructs.

La présente invention concerne des compositions et des méthodes de préparation de tissus ou de constructions tissulaires. Dans des modes de réalisation sélectionnés, l'invention concerne la construction d'une structure biologique multicouche (c'est-à-dire un système) contenant une matrice de support cellulaire ensemencée de cellules vivantes dérivées d'un tissu natif. La présente invention concerne également des protocoles de culture de tissus destinés à favoriser la croissance <i>in vitro </i>de tissus et de constructions tissulaires.

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