Composition and process - 356

C - Chemistry – Metallurgy – 07 – D

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C07D 471/04 (2006.01) A61K 31/519 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2728183

There is provided a process for the preparation of a compound of Formula 1,the use of said process in the prepara-tion of a compound of Formula 5 or a phosphate, suolphate, hydrogensulphate, malate, citrate, tartrate or fumarate salt thereof, and the use of the fumarate salt in a composition for use in therapy.

La présente invention concerne un processus de préparation d'un composé de Formule 1, l'utilisation dudit processus dans la préparation d'un composé de Formule 5 ou d'un sel phosphate, sulfate, acide sulfurique, malate, citrate, tartrate ou fumarate de ce dernier, et l'utilisation du sel fumarate dans une composition destinée à être utilisée en thérapie.

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