A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/18 (2006.01) A61L 27/12 (2006.01) A61L 27/22 (2006.01) A61L 27/24 (2006.01) A61L 31/04 (2006.01) A61L 31/12 (2006.01) A61P 19/08 (2006.01)
Patent
CA 2446840
A composition for the induction of bone growth is disclosed. The composition includes a substrate, bone growth protein, and sources of calcium and phosphate. The composition is acidic which promotes high activity of the bone growth protein. The calcium and phosphate sources can be provided as an acidic calcium phosphate salt. Also disclosed are methods of the making the composition and methods of using it.
L'invention concerne une composition favorisant la croissance osseuse. Cette composition renferme un substrat, une protéine de croissance osseuse, et des sources de calcium et de phosphate. Cette composition est acide, ce qui favorise l'activité élevée de la protéine de croissance osseuse. Les sources de calcium et de phosphate peuvent être fournies sous forme de sel de phosphate de calcium acide. Par ailleurs, l'invention concerne des méthodes de fabrication et d'utilisation de cette composition.
Benedict James D.
Thorne Kevin J.
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Centerpulse Biologics Inc.
Zimmer Orthobiologics Inc.
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