Composition and process for prevention and treatment of...

A - Human Necessities – 61 – K

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A61K 31/35 (2006.01) A61K 9/107 (2006.01) A61K 31/352 (2006.01) A61K 31/353 (2006.01)

Patent

CA 2216386

A process and pharmaceutical composition for the prevention and treatment of cutaneous Type I hypersensitivity reactions in humans is disclosed. The pharmaceutical composition comprises a chromone compound of formula (I), or a pharmacologically acceptable salt, ester or amide thereof, dissolved or dispersed in a pharmacologically acceptable carrier. In accordance with the process, a preventively or therapeutically effective amount of the composition is topically administered to a human patient, as required; i.e. for prevention the composition is administered to the area of skin susceptible to exposure to antigen and for treatment the composition is administered to the reaction site.

Procédé et composition pharmaceutique de prévention et de traitement de réactions anaphylactiques cutanées de type I chez les humains. La composition pharmaceutique consiste en un composé de chromone de formule (I), ou son sel, ester ou amide pharmacologiquement acceptable, dissous ou dispersé dans un excipient pharmacologiquement acceptable. D'après ce procédé, une quantité préventivement ou thérapeutiquement efficace de la composition est administrée de façon topique à un patient humain, suivant les besoins, c'est-à-dire qu'en usage préventif, la composition est administrée sur la zone de peau susceptible d'être exposée à l'antigène, et qu'en usage thérapeutique, la composition est administrée sur la zone de réaction.

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