A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/35 (2006.01) A61K 9/107 (2006.01) A61K 31/352 (2006.01) A61K 47/14 (2006.01)
Patent
CA 2216363
A process and pharmaceutical composition for prevention and treatment of cutaneous delayed (Type IV A) hypersensitivity reactions in humans is disclosed. The pharmaceutical composition comprises a chromone compound of formula (I), or a pharmacologically acceptable salt, ester or amide thereof, dissolved or dispersed in a pharmacologically acceptable carrier. In accordance with the process, a preventively or therapeutically effective amount of the composition is topically administered to the site of a human patient regarding such treatment, i.e. the area susceptible to exposure to antigen or the site of a cutaneous Type IV A reaction.
Ce procédé et cette composition pharmaceutique préviennent et traitent les réactions retardées (de type IV A) d'hypersensibilité cutanée. Cette composition comprend un composé à base de chromone, correspondant à la formule (I), ou un de ses sels, esters ou amides pharmacologiquement acceptables, dissous ou en dispersion dans un excipient pharmacologiquement acceptable. Selon le procédé, on administre localement une quantité préventive ou curative efficace de cette composition à l'endroit du corps d'une personne nécessitant un tel traitement, c'est-à-dire dans la zone vulnérable à une exposition à l'antigène, ou dans celle d'une réaction cutanée de type IV A.
Ahmed Mumtaz
Anaebonam Aloysius O.
Clemente Emmett
Mendes Robert W.
Ascent Pediatrics Inc.
Ascent Pharmaceuticals Inc.
Fetherstonhaugh & Co.
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